HFMSE

Hammersmith Functional Motor Scale−Expanded (HFMSE)

The HFMSE is a validated measure that has been used in several clinical studies to evaluate the motor function of children with SMA. The HFMSE adds 13 clinically relevant items from the Gross Motor Function Measure (GMFM), including lying/rolling, crawling/kneeling, standing, and walking/running/jumping. The measure has 33 items, each scored from 0 to 2. Higher scores indicate higher levels of achievement.^1,2

References

Glanzman AM, O'Hagen JM, McDermott MP, et al; the Pediatric Neuromuscular Clinical Research Network for Spinal Atrophy (PNCR), and the Muscle Study Group (MSG). Validation of the Expanded Hammersmith Functional Motor Scale in spinal muscular atrophy type II and III. J Child Neurol. 2011;26(12):1499-1507.
http://columbiasma.org/docs/HFMSE_2019_Manual.pdf (Accessed February 2020).

Adverse events should be reported to medinfohongkong@biogen.com. Additional information can be found in the package leaflet.

Biogen-176301-HKG-09/2022